Interviewing NDP Leader Jack Layton for tonight's show, "Stroumbo" had the travelling press pack in stitches.
He asked Layton if it was wise to keep saying he was going to be Prime Minister.
"Keep talking like this, people are going to think you smoke pot," said the host.
Later, Layton insisted he "didn't get into politics to be in opposition."
Not missing a beat, Stroumboulopoulos cracked: "Why did you join the NDP?"
The Hour airs at 11 pm on the CBC's main network.